Substance Abuse Treatment Center

The Center for Substance Abuse Treatment is a part of the Substance Abuse and Mental Health Services Administration. The Center for Substance Abuse Treatment is responsible for supporting treatment services through a block grant program, as well as for disseminating findings to the field and promoting the adoption of new research. The Center operates the 24-hour National Treatment Referral Hotline (1-800-662- HELP), which offers information and referral services to people seeking treatment programs and other assistance.

Medical Device Registration

Medical device registration offers a single place for patients to learn about registered devices and provides information about recalls. Medical devices include a wide range of products that vary in complexity and application. The Food and Drug Administration recognizes three classes of medical devices based on the level of control necessary in order to assure the safety and effectiveness of the device. An implant is a medical device manufactured to replace a missing biological structure, support a damaged biological structure or enhance an existing biological structure. Medical implants are manufactured devices. The surface of implants that come in contact with body might be made of a biomedical material such as titanium, silicone or apatite, depending on what is the most functional. In some cases, implants contain electronics e.g. artificial pacemaker and cochlear implants. Some implants are bioactive, such as subcutaneous drug delivery devices in the form of implantable pills or drug-eluting stents. Among the most common types of medical implants are pins, rods, screws and plates used to anchor fractured bones as they heal. There have been many examples of implant failures, including rupture of silicone breast implants, faulty hip replacement joints and breakable artificial heart valves. The consequences of implant failure depend on the critical nature of the implant and its position in the body. Thus, heart valve failure is likely to threaten the life of the individual, while breast implant or hip joint failure is less likely to be life threatening. The process of implantation of medical devices is subject to the same complications as any other invasive medical procedure, including infection, inflammation and pain. Patients also run the risk of implant rejection if the immune system of the host reacts poorly.

Vitiligo

Vitiligo or leukoderma is a chronic skin disease that causes loss of pigment, resulting in irregular pale patches of skin. The precise cause of vitiligo is complex and not fully understood. There is some evidence that suggests a combination of autoimmune, genetic and environmental factors causes vitiligo. The incidence of vitiligo worldwide is between one and two percent. According to the Diseases Database, the disorder appears in of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. The age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached. Half of the people living with vitiligo develop patches of de-pigmented skin appearing on extremities before their 20s. The patches may grow, shrink or remain constant in size. Patches often occur symmetrically across both sides on the body. Occasionally small areas may re-pigment as they are recolonised by melanocytes. The location of vitiligo affected skin changes over time, with some patches re-pigmenting and de-pigmenting.

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Coronary Heart Disease and Stroke and Weight

Coronary heart disease means that the heart and circulation blood flow are not functioning normally. Often, the arteries have become hardened and narrowed. If a person has coronary heart disease, he or she may suffer from a heart attack, congestive heart failure, sudden cardiac death, angina chest pain or abnormal heart rhythm. In a heart attack, a disruption in the flow of blood and oxygen to the heart damages portions of the heart muscle. During a stroke, blood and oxygen do not flow normally to the brain, possibly causing paralysis or death. Coronary heart disease is the leading cause of death in the United States and stroke is the third leading cause.
Overweight people are more likely to develop high blood pressure, high levels of triglycerides blood fats and LDL cholesterol, which is a fat-like substance often called bad cholesterol, and low levels of HDL cholesterol, also known as good cholesterol. High blood pressure and cholesterol are risk factors for heart disease and stroke. In addition, excess body fat may produce substances that cause inflammation. Inflammation in blood vessels and throughout the body may raise heart disease risk.
When a person loses 5 to 10 percent of his or her weight, he or she has a lower chance for developing coronary heart disease or having a stroke. If a person weighs 200 pounds, this means losing as little as 10 pounds. Weight loss may improve blood pressure, triglyceride and cholesterol levels; improve heart function and blood flow; and decrease inflammation throughout the body.